Gene Reporter Systems
ABclonal Technology Phospho-ErbB4/HER4-Y1284
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily It encodes a single-pass type I membrane protein with multiple cysteine rich domains a transmembrane domain a tyrosine kinase domain a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment Mutations in this gene have been associated with cancer Alternatively spliced variants which encode different protein isoforms have been described however not all variants have been fully characterized
ABclonal Technology Phospho-ErbB4/HER4-Y1284
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily It encodes a single-pass type I membrane protein with multiple cysteine rich domains a transmembrane domain a tyrosine kinase domain a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment Mutations in this gene have been associated with cancer Alternatively spliced variants which encode different protein isoforms have been described however not all variants have been fully characterized
System Biosciences LLC AAVS1 SAFE HARBOR SITE TARGETI
AAVS1 Safe Harbor Site Targeting Knock-in HR Donor Vector 2.0 (AAVS1-SA-puro-EF1α-MCS)
ABclonal Technology PKC zeta Rabbit pAb
Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms.
Takara Bio RetroNectin® Recombinant Human Fibronectin Fragment, 0.5 mg
A chimeric peptide of recombinant human fibronectin fragments produced in E. coli, consisting of three functional domains: a central cell-binding domain (type III repeat, 8–10), heparin-binding domain II (type III repeat, 12–14), and a CS1 site within the alternatively-spliced IIICS region. It is a 574 amino acid protein with a molecular weight of 63 kDa. When coated on the surface of containers such as culture dishes, petri dishes, flasks or bags, RetroNectin significantly enhances retrovirus-mediated gene transduction into mammalian cells. This enhancement is hypothetically due to colocalization of retroviral particles and target cells on the molecules of RetroNectin. Virus particles bind RetroNectin via interaction with heparin-binding domain II, and target cells bind mainly through the interaction of the cell surface integrin receptor VLA-4 with the fibronectin CS1 site. 0.5mg
Agilent Technologies MIRACLEHYB HYBRIDIZATION SOLU
MiracleHyb hybridization solution yields high sensitivity and lower background and makes it Easy to detect and analyze rare gene transcripts.It delivers a rapid hybridization signal, is ready to use and can be stored at room temperature
Expression Systems Baculovirus Titering Kit (includes gp64-PE antibody and Baculovirus control)
Expression Systems’ Baculovirus Titering Kit facilitates accurate determination of infectious baculovirus titers in less than 24 hours. The assay is based on detection of the baculovirus gp64 fusion protein which is expressed on the surface of infected insect cells within six hours of infection. The kit contains gp64-PE antibody and a baculovirus control of known titer.
• Reproducible and accurate titer results within 24 hours
• Measures infectious virus
• Suspension culture methodology simulates actual production conditions
• Works with any flow cytometer capable of reading samples from 96-well plates
• Flow cytometric data collection removes the operator error of counting plaques
• gp64-PE antibody can be used alone to monitor infection kinetics of baculovirus in insect cell culture
Biolegend PE/Dazzle™ 594 anti-human CD309 (VEGFR2) [A16085H]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 25 tests
PE/Dazzle™ 594 anti-human CD309 (VEGFR2) [A16085H]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 25 tests
Cell Signaling Technology PathScanR RP Total TrkA Sandwich ELISA Kit 5 Kit
PathScanR RP Total TrkA Sandwich ELISA Kit 5 Kit
Apexbio Technology LLC T7 H.Y FLUORE RNA LA. KIT 25R
T7 H.Y FLUORE RNA LA. KIT 25R APEXBIO TECHNOLOGIES
ABclonal Technology SGK1 Rabbit pAb
This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.